[Research Results] The main allergen in chicken eggs was removed using genome editing (Platinum TALEN), and its safety was confirmed. (Japanese Page)By giving back by translating the findings of our world-class research into societal benefits, we hope to make a significant impact on society and contribute to the realization of a better society.Activity reportResearchIn a joint research project conducted by Assistant Professor (Special Appointment) EZAKI Ryo and Professor HORIUCHI Hiroyuki of the Graduate School of Integrated Sciences for Life and Kewpie Corporation, they used genome (complete genetic information) editing technology to create eggs from which ovomucoid (OVM), the main allergen in chicken eggs, has been removed. Chicks from these eggs that grew into chickens were mated and laid eggs, and it was confirmed that these eggs also do not contain OVM and have no genetic abnormalities and are therefore safe. Currently, demonstration experiments are being conducted to determine how the removal of OVM affects the egg components, and what kind of processed eggs are safe to eat. This technology is also expected to be applied to medical vaccines.31Foundation and are working with the Ministry of Agriculture and Rural Development of Vietnam to open an HU satellite campus in Vietnam.Main initiativesSo that the day may come when people with egg allergies can eat eggsEnsuring safe and stable food supply to the worldEnsuring a safe and stable supply of food is essential for people to survive. HU has formulated the “President 5 Initiatives for Peace Sciences: Creating Peace to Realize Safety and Security,” which includes Food Security through Livestock Production Reforms to Improve Nutrition in the South. Discussions of food security focus on staple foods such as rice and grains, but securing eggs and dairy products, which are subject to minimal religious taboos, plays an extremely important role in improving nutrition. Therefore, HU will contribute to the supply of highly nutritious food, focusing on hen and dairy cow research, for which we maintain top level research capabilities and facilities in the country.HU has the largest experimental dairy farm in the high-temperature region of Japan, as well as facilities for raising over 40 varieties of Japanese chickens. In addition, as a next-generation smart dairy facility, its livestock barn is equipped with milking robots, feeding robots, an individual behavior management system, and a next-generation barn environmental control system, which are rare among educational and research facilities in Japan. This allows the facility to adapt to the temperature variations that are characteristic of Hiroshima Prefecture’s mountainous and hilly regions while also enabling stable milk production even as global warming progresses.We have also received a research grant from the Bill & Melinda Gates Promoting comprehensive radiation disaster managementAs a global center for radiation exposure medicine, HU has been proactively developing methods for assessing radiation exposure doses, therapeutic drugs, regenerative medicine, and more. Furthermore, we are working to establish a medical system through collaboration with external organizations such as HU Hospital and the Disaster Medical Assistance Team (DMAT). We have also been engaged in the historical verification of the experience of radiation exposure and Hiroshima’s postwar reconstruction, as well as in educational research into the most effective way of passing these on to future generations. HU has formulated the “President 5 Initiatives for Peace Sciences: Creating Peace to Realize Safety and Security,” which includes Peace through Comprehensive Radiation Disaster Management. Going forward, we will directly realize our mission of leading peace science and improve our ability to respond to radiation disasters from both medical and social science perspectives.In addition, the Radiation Effects Research Foundation (RERF) is scheduled to relocate to HU’s Kasumi Campus, with the new facility scheduled for completion in AY2026. We will work with the RERF to promote comprehensive radiation disaster management.Translating research findings into societal benefits to give back and impact society
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